Premature ovarian failure (POF), also known as primary ovarian insufficiency, is a condition where the ovaries stop functioning properly before age 40. This results in menopause-like symptoms such as hot flashes, night sweats, vaginal dryness, and irregular or absent menstrual periods.
Some key facts about POF:
Diagnosis involves blood tests for FSH, estradiol, and AMH levels. Treatment focuses on relieving symptoms and the possibility of becoming pregnant:
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The most common POF symptoms are irregular periods, hot flashes, trouble sleeping, vaginal dryness, decreased sex drive, and fertility problems. Some women also experience issues like anxiety, depression, and lack of focus. Monitoring your cycle and symptoms is important for getting an accurate POF diagnosis.
For about 75% of women with POF, the exact cause is unknown. But reasons can include previous cancer treatment, autoimmune disorders, genetic conditions, infections, or injuries to the ovaries. Our doctors can help diagnose why it's occurring early through tests like chromosome analysis and ovarian antibody blood tests.
Most women with premature ovarian failure are infertile, but pregnancy is still possible in 5-10% of POF cases. Treatment options include egg donation, embryo donation, or even stimulating your own ovaries in some situations. Discuss your family plans with a reproductive endocrinologist for personalized fertility advice.
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